- 作者：Valentina Vicennati M.D. ; a ; vicennati@aosp.bo.it"" rel=""nofollow ; Francesca Pasqui M.D.a ; Carla Cavazza M.D.a ; Silvia Garelli M.D.a ; Elena Casadio M.D.a ; Guido di Dalmazi M.D.a ; Uberto Pagotto M.D.a ; Renato Pasquali M.D.a
- 关键词：Urinary free cortisol ; Food choice ; High-density foods ; Energy intake ; Obesity
- 刊名：Nutrition
- 出版年：2011
- 出版时间：June 2011
- 年：2011
- 卷：27
- 期：6
- 页码：677-680
- 全文大小：195 K
ObjectiveThis retrospective study investigated the relation between daily urinary free cortisol excretion rate, as a marker of cortisol production rate, to daily caloric intake, food choice, body mass index (BMI), and waist circumference.Methods
One hundred twenty-seven overweight/obese women and 21 normal-weight subjects were enrolled in the study. Fasting blood samples for metabolic parameters were taken from each subject, followed by an oral glucose tolerance test. Cortisol excretion rate was assessed on 24-h urine collection (UFC/24 h). In obese patients, the daily caloric intake was calculated, and a weekly food-frequency questionnaire was assessed. Analysis of variance was used to assess the differences between groups. The relations between parameters were investigated by simple and multiple regressions.
Results
Obese women had significantly higher UFC/24 h than the normal-weight women (P < 0.001). The obese subjects had an unbalanced diet, particularly rich in saturated lipids, and weekly food choice showed a preference for highly caloric foods. UFC/24 h values and waist circumference were significantly correlated (P < 0.001), regardless of BMI. In the obese group, after adjustment for BMI, the UFC/24 h values were also significantly and positively correlated to daily carbohydrate and lipid intake and to weekly starchy food consumption.
Conclusion
We demonstrated a significant association between higher UFC/24 h and energy intake, fats, and consumption of starchy foods, and that these relations were independent of BMI.