The study population was drawn from the SAFES cohort that was formed within a national research program into the recruitment of emergency departments in 9 teaching hospitals. Subjects were to have been hospitalized in a medical ward in the same hospital as the emergency department to which they were initially admitted. Subjects who experienced NHA before emergency department admission were excluded. Those with a confirmed diagnosis of dementia were considered in the present analysis. NHA has been defined as the incident admission into either a nursing home or other long term care facility within the follow-up period. Data obtained from a Comprehensive Geriatric Assessment were used in a Cox model to predict 1-year NHA.
The 425 subjects of the study were 86 ¡À 6?years old, and were mainly women (63 % ). NHA rate was 40 % (n?= 172). Four factors were identified to increase NHA risk: age 85 or older (hazard ratio [HR]?= 1.5; 95 % confidence interval [CI]?=?1.1-2.1), inability to use the toilet (HR?= 2.5; 95 % CI?= 1.5-4.2), balance disorders (HR?= 1.5; 95 % CI?= 1.1-2.1), and living alone (HR?= 1.5; 95 % CI?=?1.1-2.1). Three factors decreased this risk significantly: inability to transfer (HR?= 0.5; 95 % CI?= 0.3-0.8), increased number of children (HR?= 0.88; 95 % CI?= 0.96-0.99), and increased initial Mini-Mental State Examination score (HR?= 0.97; 95 % CI?= 0.8-0.9).
NHA determinants in dementia are strongly linked to the patient¡¯s own characteristics but also to his or her physical or social environment. Interventions should target both members of the dyad ¡°patient-caregiver¡± because both are affected by the disease.