Neuroprotective effects of methane-rich saline on experimental acute carbon monoxide toxicity
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- 作者：Meihua Shena ; c ; 1 ; Danfeng Fanb ; 1 ; Yu Zangd ; Yan Chenc ; Kaimin Zhuc ; Zhonghai Caic ; Yueqin Liuc ; Xuejun Sune ; Jiankang Liua ; jiankangliu@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Jianfeng Gongf ; 18930173600@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：ANOVA ; analysis of variance ; CO ; carbon monoxide ; COHb ; carboxyhemoglobin ; DNS ; delayed neurological syndrome ; HBO ; hyperbaric oxygen ; &bull ; OH ; hydroxyl radical ; IL-1β ; interleukin 1 &ndash ; β ; IL-6 ; interleukin-6 ; MRS ; methane-rich saline ; MDA ; Malondialdehyde ; NS ; normal saline ; 3-NT ; 3-nitrotyrosine ; 8-OHdG ; 8-hydroxydeoxyguanosine ; ROS ; reactive oxygen species ; SOD ; superoxide dismutase ; ONOO&minus ; ; peroxynitrite ; O2&minus ; ; superoxide anion ; TBA ; thiobarbituric acid ; TNF-α ; tum
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 October 2016
- 年：2016
- 卷：369
- 期：Complete
- 页码：361-367
- 全文大小：871 K
文摘
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Methane-rich saline (MRS) can protect the brain against acute carbon monoxide (CO) poisoning induced injury.
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MRS may attenuate the oxidative stress in the brain after acute CO poisoning
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MRS may attenuate the inflammation in the brain after acute CO poisoning