- 作者：Carlos K.H. Wong ; Colman S.C. Fung ; S.C. Siu ; Yvonne Y.C. Lo ; K.W. Wong ; Daniel Y.T. Fong ; Cindy L.K. Lam
- 关键词：DM ; diabetes mellitus ; T2DM ; type 2 DM ; IFG ; impaired fasting glucose ; IGT ; impaired glucose tolerance ; 2HPPG ; two-hour post-load plasma glucose ; SMS ; short-messaging service ; FPG ; fasting plasma glucose ; BMI ; body mass index ; SBP ; systolic blood pressure ; DBP ; diastolic blood pressure ; TC ; total cholesterol ; TG ; triglycerides ; HDL-C ; high density lipoprotein cholesterol ; LDL-C ; low density lipoprotein cholesterol ; RR ; relative risk ; NNT ; the number needed to treat ; ANOVA ; analysis of variance
- 刊名：Diabetes Research and Clinical Practice
- 出版年：December, 2013
- 年：2013
- 卷：102
- 期：3
- 页码：158-166
- 全文大小：585 K
Aim
To determine the efficacy of delivering short-message service (SMS) to provide diabetes-related information in reducing the risk of developing diabetes in Chinese professional drivers with pre-diabetes.Methods
A pilot single-blinded randomized controlled trial was conducted in Hong Kong between 05/2009 and 04/2012. Professional drivers with impaired glucose tolerance (IGT) were randomly allocated to either a SMS group receiving messages comprising knowledge and lifestyle modification on diabetes or to a control group with usual care. Primary outcomes were the incidence rate of diabetes mellitus over 12 and 24 months period.
Results
Fifty-four, out of 104 professional drivers recruited, were randomly allocated to intervention group. Fewer subjects developed diabetes at 12 months in intervention group (5.56%) compared to control group (16.00%). Relative risk (RR) of diabetes onset was 0.35 (95%CI: 0.10-1.24) and the number needed to treat (NNT) for preventing one diabetes was 9.57. At 24 months, RR increased to 0.62 (95%CI: 0.24-1.61) with a NNT of 10.58. Logistic regression showed a significant odds ratio of 0.04 (P = 0.021) for intervention group compared to control group at 12-month follow-up for completers and a non-significant odds ratio of 0.34 (P = 0.303) at 24-month follow-up.
Conclusions
The SMS program proved to have potential to reduce the risk of developing diabetes at 12 months but additional measures should be integrated to prevent or delay disease progression.