Thermoresponsive mesoporous silica nanoparticles as a carrier for skin delivery of quercetin
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- 作者：Elena Ugazioa ; d ; e ; Lucia Gastaldia ; Valentina Brunellab ; d ; Dominique Scalaroneb ; d ; Sushilkumar A. Jadhavb ; d ; Simonetta Oliaro-Bossoa ; e ; Daniele Zonaria ; Gloria Berlierb ; d ; Ivana Milettoc ; Simona Sapinoa ; d ; e ; simona.sapino@unito.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：NIPAM ; Copolymer ; MCM-41 ; Biocompatibility ; Antioxidant ; Controlled release ; Cutaneous application
- 刊名：International Journal of Pharmaceutics
- 出版年：2016
- 出版时间：10 September 2016
- 年：2016
- 卷：511
- 期：1
- 页码：446-454
- 全文大小：1269 K
文摘
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Copolymer-grafted MSNs to control the release of quercetin on the skin.
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Matrix biocompatibility in vitro assessed on human keratinocyte cell line.
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Q complex antioxidant efficacy confirmed by DPPH
and Fe2+-Ferrozine assays.-
Porcine skin accumulation of Q evaluated by Franz cells.