There were significant differences in DBP formation between free and combined AAs.
Tyr–Tyr–Tyr formed more TCAN than free Tyr in chlorination due to the peptide bond.
The rank order for HAN control was permanganate > persulfate > hydrogen peroxide.
Permanganate pre-oxidation decreased HAN but increased CF during post-chlorination.
Persulfate did not increased CF and somewhat decreased HAN during post-chlorination.