Vitamin D deficiency in type 1 narcolepsy: a reappraisal

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• 作者：Yves Dauvilliers^a ; ^b ; ^{ydauvilliers@yahoo.fr} ; Elisa Evangelista^a ; Regis Lopez^a ; ^b ; Lucie Barateau^a ; ^b ; Sabine Scholz^a ; Barbara Crastes de Paulet^c ; Bertrand Carlander^a ; Isabelle Jaussent^b
• 关键词：Narcolepsy ; Vitamin D ; Hypocretin/orexin ; Sleepiness ; Autoimmunity ; Vaccination
• 刊名：Sleep Medicine
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：29
• 期：Complete
• 页码：1-6
• 全文大小：350 K
• 卷排序：29

文摘

Narcolepsy type 1 is considered an atypical immune-mediated disease in which environmental factors play a major role. Vitamin D levels and vitamin D deficiency (<75 or 50 nmol/L) did not differ between narcoleptics and controls. No association was found between vitamin D deficiency, narcolepsy duration and severity, treatment and Pandemrix® vaccination.