Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination
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- 作者：Stephanie A. Redmond1 ; Feng Mei1 ; Yael Eshed-Eisenbach2 ; Lindsay A. Osso1 ; Dena Leshkowitz3 ; Yun-An A. Shen1 ; Jeremy N. Kay4 ; Michel Aurrand-Lions5 ; David A. Lyons6 ; Elior Peles2 ; peles@weizmann.ac.il" class="auth_mail" title="E-mail the corresponding author ; Jonah R. Chan1 ; jonah.chan@ucsf.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Neuron
- 出版年：2016
- 出版时间：17 August 2016
- 年：2016
- 卷：91
- 期：4
- 页码：824-836
- 全文大小：7621 K
文摘
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Neuronal JAM2 is necessary and sufficient to inhibit myelination
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JAM2 knockout mice exhibit aberrantly myelinated neuronal cell bodies
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Myelinated neuronal cell bodies are distinctly PAX2+ inhibitory interneurons
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Oligodendrocytes utilize non-axonal inhibitory signaling in myelination