Alternative-Donor Hematopoietic Stem Cell Transplantation with Post-Transplantation Cyclophosphamide for Nonmalignant Disorders
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- 作者：Orly R. Klein ; oklein2@jhmi.edu" class="auth_mail" title="E-mail the corresponding author ; Allen R. Chen ; Christopher Gamper ; David Loeb ; Elias Zambidis ; Nicolas Llosa ; Jeffrey Huo ; Amy E. Dezern ; Diana Steppan ; Nancy Robey ; Mary Jo Holuba ; Kenneth R. Cooke ; Heather J. Symons
- 关键词：Reduced-intensity conditioning ; HLA-haploidentical ; Cyclophosphamide ; Immunodeficiency ; Bone marrow failure syndromes
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：22
- 期：5
- 页码：895-901
- 全文大小：741 K
文摘
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Reduced-intensity alternative-donor BMT can be used to treat nonmalignant disorders.
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High-dose cyclophosphamide is a safe and effective GVHD prophylaxis regimen.
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Outcomes include no TRM, no serious infections, and successful engraftment.