Sex-specific effects of docosahexaenoic acid (DHA) on the microbiome and behavior of socially-isolated mice

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• 作者：Daniel J. Davis ; PhD^a ; ¹ ; ^{davisdaniel@missouri.edu} ; Patrick M. Hecht ; PhD^b ; ¹ ; ² ; Eldin Jasarevic ; PhD^c ; David Q. Beversdorf ; MD^b ; ^d ; ^e ; ^f ; ^j ; Matthew J. Will ; PhD^b ; ^d ; ^g ; Kevin Fritsche ; PhD^h ; ⁱ ; Catherine H. Gillespie ; DVM ; PhD^a
• 关键词：Microbiome ; Docosahexaenoic acid ; Sex difference ; Anxiety ; Depression
• 刊名：Brain, Behavior, and Immunity
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：59
• 期：Complete
• 页码：38-48
• 全文大小：3020 K
• 卷排序：59

文摘

Social isolation and DHA produces sex-specific interactions with the GM. Modest amounts of DHA rapidly alter the composition and function of the GM. DHA produces sex-specific effects on anxiety- and depressive-related behaviors.