- 作者：Deborah Watkins Bruner ; deborah.w.bruner@emory.edu" class="auth_mailAuthor Vitae ; Ann O'MaraAuthor Vitae
- 关键词：Cancer clinical trials ; NCI cooperative groups ; symptom management
- 刊名：Seminars in Oncology Nursing
- 出版年：February, 2014
- 年：2014
- 卷：30
- 期：1
- 页码：4-10
- 全文大小：147 K
Objectives
To review the significant advances in cancer prevention, detection, treatment, and symptom management among the National Cancer Institute (NCI)-supported clinical trials cooperative groups, the Institute of Medicine (IOM) recommendations for restructuring of the national clinical trials infrastructure, and to discuss the contributions nurses have made in national clinical trials.Data Source
Published cooperative group manuscripts and NCI data.
Conclusion
The NCI-sponsored clinical trials cooperative groups have conducted major evidence-based, practice-changing clinical trials. Despite the advances, challenges in the process of clinical trials have caused the NCI to restructure the clinical trials network to improve efficiencies and decrease time from concept to protocol development to clinical trials completion.
Implications for Nursing Practice
Nurse investigators work with the cooperative groups for a number of reasons, including access to a large multisite population of cancer patients, making findings more generalizable. There are also increasing opportunities for areas of research including biomechanistic understanding of symptoms and symptom therapies, survivorship, and cancer care delivery.