Promotion of classic neutral bile acids synthesis pathway is responsible for cholesterol-lowing effect of Si-miao-yong-an decoction: Application of LC-MS/MS method to determine 6 major bile acids in rat liver and plasma
刊名:Journal of Pharmaceutical and Biomedical Analysis
出版年:2017
出版时间:20 February 2017
年:2017
卷:135
期:Complete
页码:167-175
全文大小:3195 K
卷排序:135
文摘
An LC–MS/MS method was established and well validated for the determination of endogenic bile acids. A new perspective to evaluate the cholesterol lowing effect of Si-miao-yong-an decoction. Quantitative method to clarify the possible mechanism. A convenient and efficient method to produce blank biological matrix by activated carbon.