Community acquired pneumonia (CAP): are doctors following the guidelines?
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- 作者：Paul Collini ; Mike Beadsworth ; Jim Anson ; Peter Burnham ; Paul Deegan ; Nick Beeching ; Alastair Miller
- 关键词：Rhino-cerebral mucormycosis ; Rhizopus oryzae ; Posaconazole
- 刊名：Journal of Infection
- 出版年：2007
- 出版时间：September 2007
- 年：2007
- 卷：55
- 期：3
- 页码：e84
- 全文大小：34 K
文摘
Mucormycosis is a potentially fatal, rapidly destructive, opportunistic infection often seen in immunocompromsied individuals and patients with diabetes mellitus. We describe two patients with rhino-orbital mucormycosis caused by Rhizopus oryzae who received posaconazole within 7 days of diagnosis and in whom cure was achieved in conjunction with extensive surgical resection of diseased tissue. Posaconazole was well-tolerated. Our experience indicates that this new extended-spectrum azole antifungal agent can be used early in the course of zygomycete infection with good results.