A light-dark shift strategy derived from light-responded metabolic behaviors for polyketides production in marine fungus Halorosellinia sp.
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- 作者：Xiaoxu Zhanga ; Hao Hea ; Ying Yina ; Weiqiang Zhoua ; Menghao Caia ; cmh022199@ecust.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xiangshan Zhoua ; Yuanxing Zhanga ; b
- 关键词：F-6-P ; fructose-6-phosphate ; F-1 ; 6-2P ; fructose-1 ; 6-bisphosphate ; PEP ; phosphoenolpyruvate ; PFK ; phosphofructokinase ; PK ; pyruvate kinase ; PDC ; pyruvate dehydrogenase complex ; PDH ; pyruvate dehydrogenase ; CS ; citrate synthase ; ICDH ; isocitrate dehydrogenase ; ACL ; ATP-citrate lyase ; ACC ; acetyl-CoA carboxylase ; ME ; malic enzyme
- 刊名：Journal of Biotechnology
- 出版年：2016
- 出版时间：10 March 2016
- 年：2016
- 卷：221
- 期：Complete
- 页码：34-42
- 全文大小：2179 K
文摘
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Light enhanced growth and polyketides production of marine fungus during 0–60 h.
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Light weakened growth and polyketides production of marine fungus during 60–120 h.
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Metabolic behaviors were deduced from enzymes activities and organic acids levels.
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A light–dark shift strategy highly improved polyketides production in bioreactor.