Research into cancer metabolomics: Towards a clinical metamorphosis
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- 作者：Orianne Olivaresa ; 1 ; J. Henry M. Dä ; britzb ; 1 ; Ayala Kinga ; Eyal Gottliebb ; e.gottlieb@beatson.gla.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Christina Halseya ; chris.halsey@glasgow.ac.uk" class="auth_mail" title="E-mail the corresponding author
- 关键词：ACSS ; acetyl-CoA synthetase ; ADI ; arginine deiminase ; AML ; acute myeloid leukaemia ; AMPK ; AMP-activated protein kinase ; ALL ; acute lymphoblastic leukaemia ; ASS ; argininosuccinate synthase ; BCAAs ; branched-chain amino acids ; BPTES ; bis-2-(5-phenylacetamido-1 ; 3 ; 4-thiadiazol-2-yl)ethyl sulphide ; 2DG ; 2-deoxyglucose ; DHFR ; dihydrofolate reductase ; DMFO ; difluoromethylornithine ; FAS ; fatty acid synthase ; FDG ; 18-fluoro-deoxyglucose ; Fd-UMP ; 5-fluoro-2&prime ; -deoxyuridine monophosphate ; 18-F-FGln ; 4-1
- 刊名：Seminars in Cell & Developmental Biology
- 出版年：2015
- 出版时间：July 2015
- 年：2015
- 卷：43
- 期：Complete
- 页码：52-64
- 全文大小：1704 K
文摘
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Metabolism-related tools are employed to diagnose and treat cancer.
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Promising metabolic tracers and anti-cancer drugs are in clinical trials.
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Metabolomics provides new information on the vulnerabilities of malignant diseases.