This paper summarizes the fundamentals of natural gas production, especially in moderate- to high-permeability reservoirs and shows the key issues in natural gas wells by performing studies in the permeability range of 0.1–100 md. Emphasis is given on the impact of turbulence and the importance of hydraulic fracturing on well deliverability for both vertical and horizontal gas wells. In addition, a design procedure for hydraulic fractures in a gas well is provided. A sample of economic evaluation is also presented to emphasize that production enhancement requires both physical and economic optimization.