Micro- and nanofluidic systems for high-throughput biological screening

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• 作者：Jongin Hong ; Joshua B. Edel ; Andrew J. deMello
• 刊名：Drug Discovery Today
• 出版年：2009
• 出版时间：February 2009
• 年：2009
• 卷：14
• 期：3-4
• 页码：134-146
• 全文大小：10426 K

文摘

High-throughput screening (HTS) is a method of scientific experimentation widely used in drug discovery and relevant to the fields of biology. The development of micro- and nanofluidic systems for use in the biological sciences has been driven by a range of fundamental attributes that accompany miniaturization and massively parallel experimentation. We review recent advances in both arraying strategies based on nano/microfluidics and novel nano/microfluidic devices with high analytical throughput rates.