Assessing Fracture Risk and Effects of Osteoporosis Drugs: Bone Mineral Density and Beyond
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- 作者：K. Shawn Davison ; David L. Kendler ; Patrick Ammann ; Douglas C. Bauer ; David W. Dempster ; Larry Dian ; David A. Hanley ; Steven T. Harris ; Michael R. McClung ; Wojciech P. Olszynski ; Chui K. Yuen
- 关键词：Antifracture treatment ; Bone mineral density ; Bone strength ; Clinical risk factors ; Osteoporosis
- 刊名：The American Journal of Medicine
- 出版年：2009
- 出版时间：November 2009
- 年：2009
- 卷：122
- 期：11
- 页码：992-997
- 全文大小：209 K
文摘
Although there have been numerous advances in the assessment of bone strength and fracture risk, the majority of these techniques can only be performed in research laboratories, making them largely unavailable to practicing clinicians. Prospective epidemiologic studies have identified risk factors that can be assessed within the clinic and combined with bone mineral density to allow clinicians to better identify untreated individuals at heightened risk for fracture and to make informed treatment decisions based on 10-year absolute fracture risk. This article discusses the assessment of fracture risk in clinical practice, reviews currently and soon-available bone measurement tools, and details the impacts of osteoporosis therapies on fracture risk.