Activity of andrographolide against dengue virus

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• 作者：Patcharee Panraksa^a ; Suwipa Ramphan^a ; Sarawut Khongwichit^a ; Duncan R. Smith^a ; ^b ; ^{duncan.smi@mahidol.ac.th} ; ^{duncan_r_smith@hotmail.com}
• 关键词：Dengue virus ; Andrographis paniculata ; Andrographolide ; Antiviral
• 刊名：Antiviral Research
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：139
• 期：Complete
• 页码：69-78
• 全文大小：3277 K
• 卷排序：139

文摘

Andrographolide has activity against dengue virus 2 with an EC50 of around 22 μM. andrographolide activity is cell type independent. andrographolide has activity against dengue virus 4. anti-DENV activity of andrographolide is confined to a post infection step.