• 作者：C. Mendoza-Edroso^a ; ^{concha.mendozaedroso@osakidetza.net} ; N. Sá ; nchez Garrido-Lestache^a ; A. Lopez-Picado^b
• 关键词：Osteoporosis ; Mujer ; Menopausia ; Consumo de fá ; rmacos
• 刊名：SEMERGEN - Medicina de Familia
• 出版年：2013
• 出版时间：April, 2013
• 年：2013
• 卷：39
• 期：3
• 页码：123-129
• 全文大小：254 K

Objetive

Estimate the percentage of excessive use of medicines (bisphosponates, strontium ranelate and raloxifene) in the prevention of fragility fractures in postmenopausal women.

Material and methods

A descriptive study conducted in an urban health centre in Vitoria-Gasteiz. The participants were women aged between 50 and 70, treated during 2010 with some of aforementioned medicines. Out of the 253 women included, three died, two moved, one did not want to sake part, and another one could not be found, leaving 246 participants. It was determinated if the treatment was or not indicated, as recommended in the ESCEO, NAMS and NOF clinical practice guides. A data search, including fragility fracture history, densitometry performed, densitometry diagnoses, prescribed medicines and prescribing doctor, was carried out by looking in the Osabide and Global Clinic digital clinic records. Interviews were carried out with 72 patients for a more complete information.

Results

The mean patient age was 60.5 ¡À 4.9 years, and 91,5 % of them (225) had undergone a densitometry. Three-quarters (75.1 % , 169) had a diagnosis of osteoporosis and 4,4 % (11) had previous history of fractures. More than a quarter (27.0 % , 68) of treatments had no indication, and varied depending of the prescribing doctor (family doctors: 8.5 % / traumatologists: 58.5 % ) (p<0.001). The use of the medicine of choice, alendronate in 29.7 % of cases, Was significantly higher (59.3 % ) in Primary Care than in other specialties.

Conclusions

A high percentage of women are given excessive medication, exposing them to potentially severe secondary damages. Family doctors deal correctly with osteoporosis, with a high percentage of indicated treatments and a rational use of medicines, with alendronate as the first choice in the majority of cases.