Female largemouth bass were fed p,p’ DDE, methoxychlor, and flutamide for three months.
These OCPs and flutamide can act to antagonize the androgen receptor.
The ovary accumulated three times more contaminant than the muscle.
Reproductive endpoints, such as oocyte development, plasma steroids and vitellogenin were not altered.
Gene network analysis suggested that the immune system may be a major target for OCPs.