Dynamics of red fluorescent dental plaque during experimental gingivitis—A cohort study

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• 作者：Monique H. van der Veen^a ; ¹ ; ^{m.vd.veen@acta.nl" class="auth_mail" title="E-mail the corresponding author} ; Catherine M.C. Volgenant^a ; ¹ ; Bart Keijser^a ; ^b ; ^c ; Jacob (Bob) M. ten Cate^a ; Wim Crielaard^a ; ^b
• 关键词：Clinical studies\trials ; Oral hygiene ; Diagnostic systems ; Imaging ; Gingivitis ; Plaque\plaque biofilms
• 刊名：Journal of Dentistry
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：48
• 期：Complete
• 页码：71-76
• 全文大小：1110 K

文摘

The dynamics of red fluorescent plaque (RFP) in comparison to clinical plaque and bleeding scores were studied during an experimental gingivitis protocol in a cohort of healthy participants.

Methods

Forty-one participants were monitored for RFP before (24 h plaque), during 14 days plaque accumulation (days 2, 5, 9, 14) and after 7 days recovery (24 h plaque). RFP was assessed on fluorescence photographs of the vestibular aspect of the anterior teeth (cuspid to cuspid) in the upper and lower jaw. Clinical plaque and bleeding were assessed at days −14, 0, 14 and 21.

Results

RFP of 24 h plaque was reproducible (days −14, 0), then increased during 14 days plaque accumulation and returned to baseline after 7 days recovery. Groups of low, moderate and high RFP formers were statistically significantly different at all times even already at baseline. The individual RFP response during 14 days plaque accumulation correlated well with RFP of 24 h plaque (days −14, 0). RFP correlated moderate to well with clinical plaque at days −14, 0, 14 and 21. From day 2 of the gingivitis challenge RFP correlated with bleeding at day 14.

Conclusions

RFP provided an objective measure of oral hygiene status. Given the correlation with clinical parameters found, the amount of RFP after 24 h plaque accumulation was indicatory for the inflammatory response during a prolonged period of no oral hygiene. This trial was registered at the public trial register ​of the Central Committee on Research Involving Human Subjects (CCMO) under number NL51111.029.14

Clinical significance

This paper shows the association between RFP after 24 h plaque accumulation and inflammatory response after a prolonged period of no oral hygiene. Red plaque fluorescence can be used to identify subjects at risk for developing gingival inflammation.