Ku antigen displays the AP lyase activity on a certain type of duplex DNA
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5">Here Ku antigen interaction with AP DNA with protruding ends is studied in details.

The efficiency of Ku cross-linking with an AP site depends on DNA structure.

5">Ku cleaves AP sites in duplex DNA with protruding ends via β-elimination.

Ku prefers apurinic sites over apyrimidinic ones.

5">Ku can initiate the repair of AP sites.

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