The effect of cyclin-dependent kinases inhibitor treatment on experimental herpes simplex encephalitis mice
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- 作者：Yu Zhou ; zhouyu131@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Yan-Ping Zeng ; Qin Zhou ; Jing-xia Guan ; Zu-Neng Lu
- 关键词：Herpes simplex encephalitis ; Cyclin-dependent kinases ; Microglia ; Inflammation
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：3 August 2016
- 年：2016
- 卷：627
- 期：Complete
- 页码：71-76
- 全文大小：1617 K
文摘
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The effect of cyclin-dependent kinases inhibitor olomoucine treatment on experimental HSE mice is explored.
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Olomoucine can induce a blunted inflammatory response and maintain the blood vessel wall intact in HSE mice.
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Olomoucine can improve neurological function and increase survival in HSE mice.