Heart rate variability in major depressive disorder and after antidepressant treatment with agomelatine and paroxetine: Findings from the Taiwan Study of Depression and Anxiety (TAISDA)
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- 作者：Ta-Chuan Yeha ; Lien-Cheng Kaob ; Nian-Sheng Tzenga ; c ; Terry B.J. Kuod ; San-Yuan Huanga ; Chuan-Chia Changa ; ; Hsin-An Changa ; chang.ha@mail.ndmctsgh.edu.tw" class="auth_mail" title="E-mail the corresponding author
- 关键词：ANOVA ; Analysis of variance ; BMI ; Body mass index ; BDI ; Beck Depression Inventory ; BAI ; Beck Anxiety Inventory ; CVD ; Cardiovascular disease ; DBP ; Diastolic blood pressure ; HRV ; Heart rate variability ; HAM-D ; Hamilton Depression Rating Scale ; HAM-A ; Hamilton Anxiety Rating Scale ; HF ; High-frequency power ; LF ; Low-frequency power ; MDD ; Major depressive disorder ; MANOVA ; Multivariate analysis of variance ; MT1 ; MT1 subtype of mela ; toninergic receptors ; MT2 ; MT2 subtype of mela ; toninergic rec
- 刊名：Progress in Neuropsychopharmacology & Biological Psychiatry
- 出版年：2016
- 出版时间：4 January 2016
- 年：2016
- 卷：64
- 期：Complete
- 页码：60-67
- 全文大小：640 K
文摘
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Previous studies have observed reduced heart rate variability (HRV) in depression.
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The effects of major depression and antidepressants on HRV were measured.
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Unmedicated patients with major depression displayed lower HRV than controls.
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Depression severity independently contributed to decreased HRV and vagal tone.
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Compared with paroxetine, agomelatine had a more vagotonic effect.