文摘
An optofluidic sensor by assembling a microfiber in lateral contact with a silica capillary in the same direction has been demonstrated for the first time. The fabrication and characteristics of the optofluidic sensor has been described and it shows a lot of advantages such as high refractive index sensitivity, high resistance to environmental perturbations, improved portability, easy fabrication and handling, and intrinsic connection to fiber-optic measurement. Its optic principle for biomolecular binding at the capillary interior has been analyzed detailedly. Its application for microRNA detection has been demonstrated.