Oxime chemistry-mediated covalent capturing on electrode surface with guanidinium recognition and application for aldolase activity assay

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• 作者：Xiaonan Wang^aAuthor Vitae ; Ying Liu^aAuthor Vitae ; Juan Zhang^a ; ^{juanzhang@shu.edu.cn}Author Vitae ; Genxi Li^a ; ^b ; ^{genxili@nju.edu.cn}Author Vitae
• 关键词：Electrochemical biosensor ; Oxime chemistry ; Guanidinium recognition ; Enzyme analysis
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：April 2017
• 年：2017
• 卷：242
• 期：Complete
• 页码：687-693
• 全文大小：1898 K
• 卷排序：242

文摘

A new strategy has been introduced for the fabrication of electrochemical biosensor. The strategy is based on the covalent capturing of molecules on electrode interface through oxime chemistry. Guanidinium recognization contributes to the excellent performance of the electrochemical biosensor. The strategy has been applied for the detection of aldolase activity. The established biosensor may be extended to other substances with chemoselective groups.