Microarray expression profile analysis of long noncoding RNAs in premature brain injury: A novel point of view
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- 作者：RJ. Chen ; L. Liu ; liuli918@163.com" class="auth_mail" title="E-mail the corresponding author ; M. Xiao ; F. Wang ; XJ. Lin
- 关键词：AD ; Alzheimer&rsquo ; s disease ; BACE1-AS ; β-secretase-1 antisense transcript ; cDNA ; complementary DNA ; FDR ; false-discovery rate ; GO ; Gene Ontology ; HE ; hematoxylin-eosin ; lncRNAs ; long noncoding RNAs ; LPS ; lipopolysaccharide ; ncRNAs ; noncoding RNAs ; PBS ; phosphate-buffered saline ; PCC ; Pearson correlation coefficients ; RVM ; random variance model ; SRY ; sex-determining region of Y chromosome ; Sox ; SRY-related HMG box ; TFs ; transcription factors
- 刊名：Neuroscience
- 出版年：2016
- 出版时间：5 April 2016
- 年：2016
- 卷：319
- 期：Complete
- 页码：123-133
- 全文大小：3524 K
文摘
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This study successfully built a premature brain injury animal model.
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The expression profile of lncRNAs in premature mice was described.
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Core regulatory lncRNAs and transcription factors were identified.
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The SRY gene may be a key transcription factor in premature brain injury.