Sex-dependent changes in neuronal morphology and psychosocial behaviors after pediatric brain injury

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• 作者：Bridgette D. Semple^a ; ^{Bridgette.Semple@unimelb.edu.au} ; Shilpi Dixit^b ; Sandy R. Shultz^a ; Wah Chin Boon^b ; Terence J. O&rsquo ; Brien^a
• 关键词：Social behavior ; Brain development ; Golgi staining ; Mouse model ; Traumatic brain injury ; Sex
• 刊名：Behavioural Brain Research
• 出版年：2017
• 出版时间：15 February 2017
• 年：2017
• 卷：319
• 期：Complete
• 页码：48-62
• 全文大小：4361 K
• 卷排序：319

文摘

Early life brain injury induces regional changes in neuronal morphology. Social behaviors were examined in male and female mice after pediatric brain injury. Sex is a determinant of both regional neuroplasticity and social outcomes. Damage to the social brain network may underlie post-injury social dysfunction.