Analytical prediction of sub-surface thermal history in translucent tissue phantoms during plasmonic photo-thermotherapy (PPTT)

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• 作者：Purbarun Dharup>1up>up> ; up>up>2up>up> ; up>up>pdhar1990@gmail.comup>up> ; up>up>purbarun@iitrpr.ac.inup> ; Anup Paulup>1up>up> ; up>up>3up>up> ; up>up>catchapu@gmail.comup> ; Arunn Narasimhan ; Sarit K. Dasup> ; up>up>skdas@iitm.ac.inup>
• 关键词：Laser hyperthermia ; Tissue mimics ; Bio heat transfer ; Gold nanostructures ; Graphene ; PPTT ; Analytical model
• 刊名：Journal of Thermal Biology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：62
• 期：part_PB
• 页码：143-149
• 全文大小：1624 K
• 卷排序：62

文摘

A semi–analytical model to predict sub–surface thermal history in translucent, soft, tissue mimics has been proposed. The anomalous thermal behaviour of occurrence of sub-surface temperature peaks is also predicted. Based on opto-thermal properties, thermal history for gold nanostructure mediated hyperthermia can be predicted. The absorbance coefficient of nano-graphene infused tissue mimics is determined theoretically and found to be appreciably accurate. A dimensionally consistent correlation to theoretically determine the position of the peak in such media is proposed.