Neurotransmitter and their metabolite concentrations in different areas of the HPRT knockout mouse brain
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- 作者：Sarah K. Tschirnera ; tschirner.sarah@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Frank Gutzkib ; gutzki.frank@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Erich H. Schneidera ; schneider.erich@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Roland Seiferta ; seifert.roland@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author ; Volkhard Kaevera ; b ; kaever.volkhard@mh-hannover.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：5-HIAA ; 5-hydroxyindoleacetic acid ; d4-dopamine ; 2-(3 ; 4-dihydroxyphenyl)ethyl-1 ; 1 ; 2 ; 2-d4-amine HCl ; d4-histamine ; histamine-d4 diHCl ; d5-DOPAC ; 3 ; 4-dihydroxyphenylacetic acid (ring-d3 ; 2 ; 2-d2) ; d6-norepinephrine ; (± ; )-norepinephrine-2 ; 5 ; 6 ; α ; β ; β-d6 HCl ; DHPG ; 3 ; 4-dihydroxyphenylethyleneglycol ; GABA ; 4-aminobutanoic acid ; HILIC ; hydrophilic interaction liquid chromatography ; HPLC ; high performance liquid chromatography ; HPRT ; hypoxanthine-guanine phosphoribosyltransferase ; HPRT&minus ;
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：365
- 期：Complete
- 页码：169-174
- 全文大小：821 K
文摘
- 5">
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5">Neurotransmitter concentrations vary in different mouse brain areas.
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Investigated neurotransmitter systems in HPRT knockout mice are unaltered.
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5">Mice may be able to partly compensate for HPRT deficiency in the brain.