Corticotrophin-releasing factor receptor 2 mediates the enhanced activation of satiety-related responses through oxytocin neurons in the paraventricular nucleus of the hypothalamus after adrenalectomy
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- 作者：Ernane Torres Uchoaa ; b ; ernane_uchoa@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; Rodrigo Roratoa ; Silvia Graciela Ruginska ; c ; Beatriz de Carvalho Borgesa ; Jose Antunes-Rodriguesa ; Lucila L.K. Eliasa
- 关键词：ADX ; adrenalectomy ; B ; corticosterona ; CRF ; corticotrophin-releasing factor ; OT ; oxytocin ; PVN ; paraventricular nucleus of the hypothalamus ; NTS ; nucleus of the solitary tract ; TBE ; 2 ; 2 ; 2-tribromoethanol ; i.p. ; intraperitoneal ; PaPo ; posterior parvocellular subdivisions of the PVN ; PaMP ; medial parvocellular subdivisions of the PVN ; PB ; phosphate buffer ; DAB ; diaminobenzidine hydrochloride ; AS30 ; d-Phe11 ; His12-Sauvagine 11-40 ; Antisauvagine-30
- 刊名：Neuroscience Letters
- 出版年：2015
- 出版时间：8 October 2015
- 年：2015
- 卷：606
- 期：Complete
- 页码：123-128
- 全文大小：1337 K
文摘
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ADX increases OT neuronal activation in the PVN in response to feeding.
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CRFr2 blockade reduces the high activation of PVN OT neurons after meal in ADX rats.
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PVN OT neurons might be downstream mediators of CRF on satiety responses after ADX.