Understanding the molecular mechanisms of NETs and their role in antiviral innate immunity

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• 作者：Juan Manuel Agraz-Cibrian^a ; ¹ ; ^{jumaagci@gmail.com} ; Diana M. Giraldo^b ; ¹ ; ^{diana2g@gmail.com} ; Fafutis-Morris Mary^c ; ^{mfafutis@gmail.com} ; Silvio Urcuqui-Inchima^b ; ^{silviourcuqui@gmail.com}
• 关键词：Neutrophil extracellular traps ; Virus ; Innate response ; Inflammation ; Cytokines
• 刊名：Virus Research
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：228
• 期：Complete
• 页码：124-133
• 全文大小：1433 K
• 卷排序：228

文摘

Activated neutrophils can release NETs. NETs are formed by proteases, chromatin, and antimicrobial proteins. The main function of NETs is to trap and kill microbes avoiding their scatter. Virus are able to induce NET formation by human neutrophils in vitro.