The continuous kilogram-scale process for the synthesis of 2,4,5-trifluorobromobenzene via Gattermann reaction using microreactors

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• 作者：Qiulin Deng^a ; ^b ; ^{qiulindeng@swust.edu.cn} ; Qin Lei^b ; Ruwei Shen^a ; Chao Chen^a ; Lixiong Zhang^a ; ^{lixiongzhang@yahoo.com}
• 关键词：2 ; 4 ; 5-Trifluorobromobenzene ; Microflow ; Gattermann reaction ; Diazonium salts
• 刊名：Chemical Engineering Journal
• 出版年：2017
• 出版时间：1 April 2017
• 年：2017
• 卷：313
• 期：Complete
• 页码：1577-1582
• 全文大小：725 K
• 卷排序：313

文摘

Efficient flow process for producing 2,4,5-trifluorobromobenzene in high yield and high selectivity. Efficient kilogram-scale synthetic route for 2,4,5-trifluorobromobenzene. Provides an easily assembled micro- and batch reactor tandem model for liquid/liquid and liquid/solid reactions.