Newly-generated Al(OH)₃-supported Pd nanoparticles-catalyzed Stille and Kumada coupling reactions of diazonium salts, (Het)aryl chlorides

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• 作者：Xing Li ; ^{lixing@tyut.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Tingting Zhu ; Zhongqi Shao ; Yingjun Li ; Honghong Chang ; Wenchao Gao ; Yongli Zhang ; Wenlong Wei ; ^{weiwenlong@tyut.edu.cn" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Pd/Al(OH)3 ; Nanoparticles ; Stille ; Kumada ; Diazonium salts
• 刊名：Tetrahedron
• 出版年：2016
• 出版时间：7 January 2016
• 年：2016
• 卷：72
• 期：1
• 页码：69-75
• 全文大小：1204 K

文摘

A ligand-free Pd/Al(OH)₃ nano-catalyst which is prepared by one-pot three-component method using Pd(PPh₃)₄, tetra (ethylene glycol), and aluminum tri-sec-butoxide exhibits excellent catalytic activity in Stille cross-couplings of (Het)aryl chlorides, arenediazonium tetrafluoroborate salts with phenyltributylstannane, respectively, and Kumada couplings of (Het)aryl chlorides with various Grignard reagents. More importantly, these two processes show excellent functional group compatibility with moderate to good yields and they are also versatile with respect to not only (Het)aryl chlorides, but also diazonium salts, and heteroaryl Grignard reagents. The nano-catalyst could also be recycled and reused 5 times without loss of activity and decrease of yield.