Ligularia fischeri and its constituent 3,4-dicaffeoylquinic acid improve obesity-induced nonalcoholic fatty liver disease by regulating lipid metabolism and activating AMPK

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• 作者：Ahmad Randy^a ; ^b ; Myungsuk Kim^a ; ^c ; Chu Won Nho^a ; ^c ; ^{cwnho@kist.re.kr}
• 关键词：Fatty liver disease ; Metabolic disorders ; Ligularia fischeri ; 3 ; 4-dicaffeoylquinic acid ; AMP-activated protein kinase
• 刊名：Journal of Functional Foods
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：27
• 期：Complete
• 页码：1-16
• 全文大小：2566 K
• 卷排序：27

文摘

Ligularia fischeri suppressed lipid accumulation and activated AMPK in HepG2 cells. L. fischeri inhibited liver injury and steatosis in HFD-induced mice L. fischeri reduced oxidative stress and insulin resistance in HFD-induced mice