PEG-based autonomous capillary system with integrated microbead array for immunoassay
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- 作者：Qingdi Zhua ; qingdi@smart.mit.edu" class="auth_mail" title="E-mail the corresponding author ; Dieter Traub ; c ; bietrau@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author
- 关键词：Capillary system ; PEG based material ; Microbead array ; Immunoassay ; Tumor markers ; Point-of-care test
- 刊名：Materials Science & Engineering C
- 出版年：2017
- 出版时间：1 January 2017
- 年：2017
- 卷：70
- 期：part_P2
- 页码：1031-1038
- 全文大小：977 K
文摘
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Facile fabrication of PEG based capillary system (CS) by photopolymerization
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Autonomous flow on CS tunable by one-step modification with surfactant solution
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Polyacrylamide gel pad integration enables bead-based autonomous immunoassays.
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LODs for two tumor makers are lower than their clinical threshold level.
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Multiplex, quantitative assay achieved using a spatially encoded microbead array.