Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome
详细信息 查看全文
- 作者：Madlen Loebela ; madlen.loebel@charite.de" class="auth_mail" title="E-mail the corresponding author ; Patricia Grabowskia ; Harald Heideckeb ; Sandra Bauera ; Leif G. Hanitscha ; Kirsten Wittkea ; Christian Meisela ; c ; Petra Reinked ; e ; Hans-Dieter Volka ; e ; Ø ; ystein Flugef ; Olav Mellaf ; g ; Carmen Scheibenbogena ; e
- 关键词：AChR ; acetylcholine receptor ; AdR ; adrenergic receptors ; ANA ; anti-nuclear antibodies ; CFS ; Chronic Fatigue Syndrome ; GPCR ; G-protein coupled receptor ; POTS ; Postural Orthostatic Tachycardia Syndrome ; RRTI ; Recurrent respiratory tract infections ; TG ; thyreoglobulin ; TPO ; thyreoperoxidase
- 刊名：Brain, Behavior, and Immunity
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：52
- 期：Complete
- 页码：32-39
- 全文大小：1969 K
文摘
- •
β AdR and muscarinic AChR autoantibodies are elevated in a subset of patients with CFS.
- •
High autoantibodies correlate with elevated IgG1–3, TPO and ANA antibodies and T cell activation.
- •
In patients responding to rituximab high pretreatment autoantibodies declined after treatment.