Inhibition of diethylnitrosamine-induced liver cancer in rats by Rhizoma paridis saponin
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- 作者：Jing Liua ; b ; Shuli Mana ; b ; msl@tust.edu.cn" class="auth_mail" title="E-mail the corresponding author ; man1983000@163.com" class="auth_mail" title="E-mail the corresponding author ; Jing Lia ; Yang Zhanga ; Xin Menga ; Wenyuan Gaoc ; biochemgao@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：AFP ; alpha-fetoprotein ; ALB ; albumin ; ALP ; alkaline phosphatase ; CAT ; catalase ; CHE ; cholinesterase ; DBIL ; direct bilirubin ; DEN ; diethylnitrosamine ; GGT ; γ-glutamyltransferase ; GLB ; globulin ; GSH ; reduced glutathione ; GST ; glutathione S-transferase ; HCC ; hepatocellular carcinoma ; 8-OHdG ; 8-hydroxy-deoxyguanosine ; IBIL ; indirect bilirubin ; MDA ; malondialdehyde ; NO ; nitric oxide ; ROS ; reactive oxygen species ; RPS ; Rhizoma Paridis saponin ; SOD ; ssuperoxide dismutases ; TBA ; total bile acid ; TBIL ; t
- 刊名：Environmental Toxicology and Pharmacology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：46
- 期：Complete
- 页码：103-109
- 全文大小：2170 K
文摘
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RPS alleviated levels of liver injury.
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RPS increased mRNA levels of phase I and II to induce the byproducts exreation.
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RPS acted anti-oxidant and decreased DNA damage in DEN-induced rats.