Splicing factor proline/glutamine-rich is a novel autoantigen of dermatomyositis and associated with anti-melanoma differentiation-associated gene 5 antibody

详细信息    查看全文

• 作者：Yuji Hosono^a ; ^{hosono25@kuhp.kyoto-u.ac.jp} ; Ran Nakashima^a ; ^{ranran@kuhp.kyoto-u.ac.jp} ; Satoshi Serada^b ; ^{serada@nibiohn.go.jp} ; Kosaku Murakami^a ; ^{kosaku@kuhp.kyoto-u.ac.jp} ; Yoshitaka Imura^a ; ^{imuray@kuhp.kyoto-u.ac.jp} ; Hajime Yoshifuji^a ; ^{yossii@kuhp.kyoto-u.ac.jp} ; Koichiro Ohmura^a ; ^{ohmurako@kuhp.kyoto-u.ac.jp} ; Tetsuji Naka^b ; ^{tnaka@nibiohn.go.jp} ; Tsuneyo Mimori^a ; ^{mimorit@kuhp.kyoto-u.ac.jp}
• 关键词：SFPQ ; MDA5 ; Myositis ; Antibody ; CADM ; Virus
• 刊名：Journal of Autoimmunity
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：77
• 期：Complete
• 页码：116-122
• 全文大小：745 K
• 卷排序：77

文摘

SFPQ is a novel autoantigen for dermatomyositis (DM). All anti-MDA5-positive patients who showed recurrence of DM/CADM had anti-SFPQ. Diagnosis timing had seasonality according to the timing of anti-SFPQ appearance.