Sustained drug release and electrochemical performance of ethyl cellulose-magnesium hydrogen phosphate composite

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• 作者：Faruq Mohammad^a ; ^{fmohammad@ksu.edu.sa} ; Tanvir Arfin^b ; ^{t_arfin@neeri.res.in} ; Hamad A. Al-Lohedan^a
• 关键词：EC ; ethyl cellulose ; MgHPO4 ; magnesium hydrogen phosphate ; CBPC ; chemically bonded phosphate ceramics ; XRD ; x-ray diffraction ; EDAX ; electron diffraction analysis by x-rays ; FT-IR ; fourier transform-infrared ; HRTEM ; high resolution transmission electron microscopy ; SEM ; scanning electron microscopy
• 刊名：Materials Science and Engineering: C
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：71
• 期：Complete
• 页码：735-743
• 全文大小：1434 K
• 卷排序：71

文摘

Porous nature of ethyl cellulose and the crystal structure of MgHPO4 after the composite formation were investigated. Conductivity studies proved that the composite is electrically conductive and the conductivity is strongly influenced by the electrolyte type as see the conductivity order to be K+ > Na+. Composite can take up to 80% of Proguanil used for loading and can release up to 87% from it under neutral conditions in just over a 90 min period. Due to the absence of toxicity on in vitro cell culture systems, the composite can be applied for sustainable drug delivery and biosensor related applications.