刊名:Biochemical and Biophysical Research Communications
出版年:2017
出版时间:29 January 2017
年:2017
卷:483
期:1
页码:359-365
全文大小:2463 K
卷排序:483
文摘
We produced Cyp27b1−/− mice and analyzed their phenotypes. Vdr−/− mice exhibited alopecia and Cyp27b1−/− mice exhibited cartilage dysplasia. Maintenance of the hair cycle is associated with 25D3 via Vdr. 1α,25D3 controls chondrocyte proliferation and differentiation independent of Vdr.