The dissimilar time course of temporary threshold shifts and reduction of inhibition in the inferior colliculus following intense sound exposure
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- 作者：A.N. Heeringa
- 关键词：ABR ; auditory brainstem response ; ANOVA ; analysis of variance ; CF ; characteristic frequency ; fMRI ; functional magnetic resonance imaging ; GABA ; 纬-aminobutyric acid ; IC ; inferior colliculus ; PSTH ; post-stimulus time histogram ; RM-ANOVA ; repeated measures analysis of variance ; SEM ; standard error of the mean ; SPL ; sound pressure level ; SpO2 ; blood oxygen saturation
- 刊名：Hearing Research
- 出版年：June 2014
- 年：2014
- 卷：312
- 期：Complete
- 页码：38-47
- 全文大小：2035 K
文摘
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- <p id="p0010">Threshold shifts from a free field exposure to 11 kHz of 124 dB SPL recover in one week.p>
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- <p id="p0015">ABR wave I amplitude is chronically reduced, but wave IV recovers in a week.p>
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- <p id="p0020">Spontaneous rates of inferior colliculus neurons are unaffected.p>
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- <p id="p0025">Stimulus-evoked inhibition was reduced but recovered within two to four weeks.p>
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- <p id="p0030">The increased central gain suggests a possible mechanism for hyperacusis.p>