To test segmental LPSS for predicting LVWM abnormalities in routine echocardiography laboratory practice.
LVWM was evaluated by an experienced cardiologist, during routine practice, in 620 patients; segmental LPSS values were then calculated.
In this work, reflecting real life, 99.6% of segments were successfully tracked. Mean (95% confidence interval [CI]) segmental LPSS values for normal basal (n = 3409), mid (n = 3468) and apical (n = 3466) segments were –16.7% (–16.9% to –16.5%), –18.2% (–18.3% to –18.0%) and –21.1% (–21.3% to –20.9%), respectively. Mean (95% CI) segmental LPSS values for hypokinetic basal (n = 114), mid (n = 116) and apical (n = 90) segments were –7.7% (–9.0% to –6.3%), –10.1% (–11.1% to –9.0%) and –9.3% (–10.5% to –8.1%), respectively. Mean (95% CI) segmental LPSS values for akinetic basal (n = 128), mid (n = 95) and apical (n = 91) segments were –6.6% (–8.0% to –5.1%), –6.1% (–7.7% to –4.6%) and –4.2% (–5.4% to –3.0%), respectively. LPSS allowed the differentiation between normal and abnormal segments at basal, mid and apical levels. An LPSS value ≥ –12% detected abnormal segmental motion with a sensitivity of 78% for basal, 70% for mid and 82% for apical segments.
Segmental LPSS values may help to differentiate between normal and abnormal left ventricular segments.