3-(Phenyl-4-oxy)-5-phenyl-4,5-dihydro-(1H)-pyrazole: A fascinating molecular framework to study the enantioseparation ability of the amylose (3,5-dimethylphenylcarbamate) chiral stationary phase. Part I. Structure-enantioselectivity relationships
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- 作者：Simone Carradoria ; Marco Pierinib ; Sergio Mentab ; Daniela Seccib ; Rossella Fioravantib ; Roberto Cirillic ; rcirilli@iss.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：Enantiomer separation ; Receptorial-like enantioselectivity ; Chiral stationary phase ; Chiralpak AD-3 ; Structure-enantioselectivity relationships ; Solvophobic interaction
- 刊名：Journal of Chromatography A
- 出版年：2016
- 出版时间：7 October 2016
- 年：2016
- 卷：1467
- 期：Complete
- 页码：221-227
- 全文大小：1052 K
文摘
- 5">
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5">This paper describes the HPLC enantioseparation of a set of six chiral pyrazolines on the IA-3 CSP.
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By using pure methanol as a mobile phase an α = 50 was observed for one of them.
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5">HPLC data suggested the involvement of solvophobic interactions in the unusual recognition mechanism.