Lifestyle Choices Fuel Epidemics of Diabetes and Cardiovascular Disease Among Asian Indians

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• 作者：Evan L. O&rsquo ; Keefe^a ; ^b ; James J. DiNicolantonio^c ; Harshal Patil^c ; John H. Helzberg^d ; Carl J. Lavie^b ; ^{clavie@ochsner.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：CAD ; coronary artery disease ; CI ; confidence interval ; CV ; cardiovascular ; CVD ; cardiovascular disease ; HFCS ; high fructose corn syrup ; MetS ; metabolic syndrome ; NAFLD ; non-alcoholic fatty liver disease ; NCD ; non-communicable disease ; PA ; physical activity ; RR ; risk ratio ; T2DM ; type 2 diabetes mellitus ; US ; United States ; VDD ; vitamin D deficiency ; WHO ; World Health Organization
• 刊名：Progress in Cardiovascular Diseases
• 出版年：2016
• 出版时间：March-April 2016
• 年：2016
• 卷：58
• 期：5
• 页码：505-513
• 全文大小：960 K

文摘

Within the next 15 years, India is projected to overtake China as the world's most populous nation. Due to the rapid pace of urbanization and modernization fueling population growth, in conjunction with a genetic predisposition to insulin resistance, India is suffering a rising epidemic of non-communicable diseases (NCDs), including coronary artery disease (CAD), type 2 diabetes mellitus (T2DM), and stroke. In addition to the genetic predisposition, major negative lifestyle factors are contributing to the alarming outbreak of cardiovascular disease (CVD) among the Asian Indian population; these factors include: 1) a diet high in added sugar, refined grains and other processed foods, 2) physical inactivity, 3) vitamin D deficiency (VDD), and 4) smoking/pollution. These risk factors are all highly modifiable, and steps to improve these issues should be taken urgently to avoid a worsening NCD crisis among the inhabitants of the South Asian subcontinent as well as for people with Asian Indian ethnicity worldwide.