Critical role of Casein kinase 2 in hepatitis C NS5A-mediated inhibition of Kv2.1 K+ channel function
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- 作者：Katerina Clemens ; Chung-Yang Yeh ; Elias Aizenman ; redox@pitt.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Neuroscience Letters
- 出版年：2015
- 出版时间：16 November 2015
- 年：2015
- 卷：609
- 期：Complete
- 页码：48-52
- 全文大小：769 K
文摘
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Neurons expressing NS5A1b have decreased Kv2.1-mediated K+ currents.
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Casein kinase 2 inhibition blocks K+ current modulation by NS5A1b.
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Casein kinase 2 inhibition potentiates K+ currents.
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Ledipasvir treatment does not block NS5A1b’s modulation of Kv2.1 function.