Bone loss and wrist fractures after withdrawal of hormone therapy: The 15-year follow-up of the OSTPRE cohort
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- 作者：Jarmo Saarelainena ; jtsaarel@student.uef.fi" class="auth_mail" title="E-mail the corresponding author ; Saara Hassia ; Risto Honkanena ; b ; Heli Koivumaa-Honkanenb ; c ; d ; Joonas Sirolaa ; e ; Heikki Krö ; gera ; e ; Marja H. Komulainenf ; Marjo Tuppurainena ; f
- 关键词：Bone mineral density ; Hormone therapy ; Postmenopausal ; Wrist fracture ; Cohort study ; Longitudinal
- 刊名：Maturitas
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：85
- 期：Complete
- 页码：49-55
- 全文大小：1216 K
文摘
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Long-term HT-use protects from bone loss and wrist fracture, reducing, thus, the incidence of osteopenia and osteoporosis.
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HT-use of less than 5 years does not have long-term bone protection.
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The three main reasons for discontinuation of HT were resolution of menopausal symptoms, disease and fear of adverse effects or cancer.