Diphenyl diselenide supplementation in infected mice by Toxoplasma gondii: Protective effect on behavior, neuromodulation and oxidative stress caused by disease
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- 作者：Vanessa Schopf Machadoa ; b ; Nathieli B. Bottarib ; Matheus D. Baldisseraa ; Virginia C. Rechc ; Francine R. Ianiskic ; Cristiane Signorb ; Maribel A. Rubinb ; Emily P. Waczukf ; Claiton I. Schwertze ; Ricardo E. Mendese ; Giovana Camillog ; Fernanda F. Vogelg ; Mario L. de la Ruea ; Vera M. Morschb ; Maria Rosa C. Schetingerb ; Pâ ; mella K.S. Frü ; haufh ; Aleksandro S. Da Silvab ; d ; aleksandro_ss@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Toxoplasmosis ; Energy metabolism ; Acetylcholine ; ATP ; (PhSe)2
- 刊名：Experimental Parasitology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：169
- 期：Complete
- 页码：51-58
- 全文大小：1276 K
文摘
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Toxoplasmosis is an important infectious disease in humans and animals.
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T. gondii infection causes pathological and behavioral changes in the brain.
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(PhSe)2 was able to modulate enzymes related to energy metabolism in the brain.
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(PhSe)2 modulate AK, CK and AChE in the brain.
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The treatment with (PhSe)2 showed antioxidant effect.