Physicochemical investigation of antibacterial Moxifloxacin interacting with quaternary ammonium disinfectants
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- 作者：Muhammad Faizan Nazara ; faizan_qau@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; faizan.nazar@uog.edu.pk" class="auth_mail" title="E-mail the corresponding author ; Fareeha Mukhtara ; Muhammad Ashfaqa ; Hafiz Muhammad Abd Ur Rahmanb ; Muhammad Naveed Zafara ; Sajjad Hussain Sumrraa
- 关键词：Quaternary ammonium disinfectants ; Cationic surfactants ; Hydrophobic head group ; Molecular recognition ; Phospholipid membrane models
- 刊名：Fluid Phase Equilibria
- 出版年：2015
- 出版时间：25 November 2015
- 年：2015
- 卷：406
- 期：Complete
- 页码：47-54
- 全文大小：811 K
文摘
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Molecular interactions of antibacterial Moxifloxacin with quaternary ammonium disinfectants are described.
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The extent of drug partitioning into surfactant assemblies is exclusively mechanized.
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The solubilization of drug can be modulated by the variation of pH and hydrophobic head group.